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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

The Sinclair Method vs Abstinence: Which Path to Recovery is Right for You?

The Sinclair Method vs Abstinence: Which Path to Recovery is Right for You?

The Sinclair Method vs Abstinence: Which Path to Recovery is Right for You?Bruce Rose
Published on: 15/09/2025

When we talk about recovery from alcohol use disorder (AUD), most people still think of abstinence — the complete and permanent cessation of drinking. It's the traditional approach taken by many rehab centres and support groups like Alcoholics Anonymous.

The Sinclair Method (TSM)
Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair Method

Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair Method

Could This £3 Pill Be the Answer? What Recent Newspapers Are Saying About Naltrexone and The Sinclair MethodBruce Rose
Published on: 05/09/2025

Over the past few months, major UK tabloids like The Sun have published several high-profile stories on naltrexone — a £3 tablet nicknamed the "Ozempic for drinkers". It’s been hailed by some as a revolutionary option for those wanting to cut back or quit alcohol.

The Sinclair Method (TSM)
Does The Sinclair Method Work? Exploring Its Success and Science

Does The Sinclair Method Work? Exploring Its Success and Science

Does The Sinclair Method Work? Exploring Its Success and ScienceBruce Rose
Published on: 04/09/2025

The Sinclair Method (TSM) is a medication-based treatment for Alcohol Use Disorder (AUD) that allows individuals to continue drinking while retraining their brain’s response to alcohol. The cornerstone of this method is naltrexone, an opioid blocker that dulls the endorphin rush typically triggered by alcohol.

The Sinclair Method (TSM)
Dr David Sinclair: The Research Legacy Behind The Sinclair Method

Dr David Sinclair: The Research Legacy Behind The Sinclair Method

Dr David Sinclair: The Research Legacy Behind The Sinclair MethodBruce Rose
Published on: 11/06/2025

The Sinclair Method didn’t originate in a corporate lab or a detox facility—it started in a Helsinki research centre. Dr John David Sinclair, a behavioural psychologist from the United States, moved to Finland in the early 1970s after completing his PhD. There, he joined Alko Laboratories, the research arm of Finland’s state alcohol monopoly, which would later become part of the country’s National Public Health Institute.

The Sinclair Method (TSM)
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